haploidentical-transplant

Haploidentical Stem Cell Transplant

Advanced Allogeneic Stem Cell Therapy and Care

A haploidentical stem cell transplant is an allogeneic procedure using healthy blood-forming stem cells from a partially matched family donor (such as a parent, child, or sibling sharing about half of the patient's HLA markers). It is a vital treatment option for patients who do not have a fully matched donor, particularly for selected blood cancers and bone marrow disorders.

At EthosMedi, we guide patients through donor matching, eligibility, and comprehensive treatment support.

How Does a Haploidentical Transplant Work?

• Donor Selection & HLA Testing: Assessing family members for compatibility and tissue typing.

• Pre-Transplant Evaluation: Checking overall health, organ function, and readiness.

• Conditioning Treatment: Chemotherapy or radiation to prepare the body for donated cells.

• Stem Cell Infusion: Administering the donor's stem cells via an intravenous (IV) line.

• Engraftment & Monitoring: Tracking blood counts, infection signs, and new cell growth.

Conditions Treated with Haploidentical Transplants

• Leukemia: Selected blood cancers like acute myeloid and acute lymphoblastic leukemia.

• Lymphoma: Specific cases of Hodgkin and non-Hodgkin lymphoma.

• Myelodysplastic Syndromes (MDS): Conditions where bone marrow produces abnormal cells.

• Aplastic Anemia: Selected cases of severe bone marrow failure.

Recovery and Post-Transplant Care

Recovery requires close medical supervision as blood counts remain temporarily low.

• Infection Prevention & Testing: Regular blood tests and strict hygiene measures.

• Managing GVHD Risks: Specialized protocols to monitor and control graft-versus-host disease (where donor cells react against recipient tissues).

• Healing Timeline: Full immune system recovery can take several months, making ongoing follow-up essential.

When a fully matched donor is not available, exploring suitable alternatives can open another path to transplant care